Kevin de Bruyne is set to miss Manchester City's Premier League clash with Arsenal on Saturday.
De Bruyne suffered a muscle injury in Belgium's 2-1 defeat to England at Wembley on Sunday and was substituted late on.
The PFA Player of the Year withdrew from the Belgium squad to face Iceland and has returned to City for treatment from their medical team.
Roberto Martinez had claimed "it was more precaution that we had to avoid [something], he wasn't 100% percent."
Sources close to De Bruyne revealed the injury is not serious, but is likely to keep him out of the Arsenal game.
City are unwilling to risk playing him and potentially losing him for longer.
Against that backdrop, De Bruyne is likely to be left out as a precaution, leaving him time to fully recover for City's opening Champions League group game at home to Porto next Wednesday.
De Bruyne, 29, warned that many more players will get injured this season, because of the lack of a proper rest during the off-season, because of the disruption caused by the coronavirus pandemic.
City are 14th in the Premier League table with four points from their first three games.
Guardiola's side were held to a 1-1 draw by Leeds United in their last outing.
They face Mikel Arteta's men who have taken nine points from their opening four games.
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